Medical cannabis for fibromyalgia: the short answer
Medical cannabis may reduce pain for some people with fibromyalgia. The evidence is limited. No cannabis product is FDA-approved for fibromyalgia. Talk to a doctor before you try it.
What fibromyalgia is
Fibromyalgia causes widespread pain, fatigue, and sleep problems. About 4 million US adults have fibromyalgia. That is 2% of the adult population. Women are diagnosed more than men. The cause is unknown.
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What research shows
Studies on cannabis for fibromyalgia are small and short. A 2020 review in Pain Medicine looked at 11 studies. The review found low-quality evidence. Some patients reported less pain. Other patients reported no change. Placebo effects are strong in fibromyalgia trials.
THC and CBD act on different targets. THC binds to CB1 receptors in the brain. CBD does not cause a high. CBD may reduce anxiety and inflammation in animal studies. Human data for fibromyalgia is thin.
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Risks and side effects
- Dizziness
- Dry mouth
- Fatigue
- Memory problems
- Coordination problems
THC can impair driving. Cannabis can interact with duloxetine, pregabalin, and amitriptyline. These drugs treat fibromyalgia. Talk to a pharmacist about interactions.
Legal status in the US
Medical cannabis is legal in 38 states as of 2024. Rules differ by state. Some states list fibromyalgia as a qualifying condition. Other states do not. A doctor's recommendation is required in most states. Cannabis remains illegal under federal law.
CBD products
CBD products sold online contain variable doses. The FDA does not check CBD products for purity. Look for a certificate of analysis from a third-party lab. That document shows cannabinoid levels and contaminant tests.
Talk to a doctor
Ask your doctor about cannabis for fibromyalgia. A doctor can review your medicines and health history. Standard treatments include exercise, cognitive behavioral therapy, and drugs like duloxetine. Cannabis may help as an add-on. It is not a cure.